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But some bodybuilders supplement with IGF-1 in hopes of gaining more strength (7, 9)and improving their appearance. Unfortunately, supplementing with IGF-1 can have a negative effect on athletes, as well. IGF-1 has a role in stimulating a person's growth hormones, which stimulates muscle growth, which accelerates the body's response to anabolic hormones, as well as fat loss, which can burn fat (10). IGF-1 is a naturally occurring protein. The body converts it within hours into growth hormone, muscle growth stimulating hormone, anabolic hormones that enhance muscle growth (11). In research funded by the National Institutes of Health, it has been shown that IGF-1 has no effect on muscle strength, endurance or metabolism (12). There is a reason why IGF-1 supplements have no positive effect on bodybuilders or people who want to improve athletic performance. Studies on IGF-1 The use of IGF-1 supplements has been criticized for the fact that the protein in the product has been depleted. Some suggest that this is due to the fact that people can't get the body's natural production of IGF-1 from their diet (13). However, studies show that people supplementing with IGF-1 are able to get the same levels of growth hormone as those who are taking the protein protein alone (14). A 2004 meta-analysis of eight trials with more than 40,000 patients found that IGF-1 supplements are no better than a placebo when it comes to increasing strength in non-athletes. The review also reviewed studies that evaluated the anti-aging effect of insulin-like growth factor-1. This is different from the anabolic effects, which are what is measured. Insulin-like growth factor-1 boosts the growth of muscle tissue and bone growth, but does not promote muscle mass in bodybuilders or those who are trying to improve athletic performance (15). The study's author, Andrew Weil of the University of Toronto, also noted that IGF-1 is "an anti-inflammatory," something that will not help people reduce body fat or lose body fat. If you're new to IGF-1 supplements, it's best to not use them for any reason other than that they can increase bodyweight. It's important to realize that only people with severe conditions like lupus are at risk for IGF-1 toxicity. For more information about IGF-1 supplements, check out the links below: References Related Article:
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